Positive Feedbacks of Coagulation
نویسندگان
چکیده
منابع مشابه
Positive feedbacks of coagulation: their role in threshold regulation.
Tissue factor (TF), the initiator of coagulation, continuously circulates in the plasma, and the clotting system "idles," generating very low levels of active clotting enzymes, clotting products, and by-products. Given the enormous amplification potential of the clotting cascade, rigorous control is required to ensure that such low-level stimulation does not cause massive system amplification a...
متن کاملMathematical analysis of activation thresholds in enzyme-catalyzed positive feedbacks: application to the feedbacks of blood coagulation.
A hierarchy of enzyme-catalyzed positive feedback loops is examined by mathematical and numerical analysis. Four systems are described, from the simplest, in which an enzyme catalyzes its own formation from an inactive precursor, to the most complex, in which two sequential feedback loops act in a cascade. In the latter we also examine the function of a long-range feedback, in which the final e...
متن کاملAlternative states and positive feedbacks in restoration ecology.
There is increasing interest in developing better predictive tools and a broader conceptual framework to guide the restoration of degraded land. Traditionally, restoration efforts have focused on re-establishing historical disturbance regimes or abiotic conditions, relying on successional processes to guide the recovery of biotic communities. However, strong feedbacks between biotic factors and...
متن کاملRegional Climate Change Policy under Positive Feedbacks and Strategic Interactions
The surface albedo feedback along with heat and moisture transport from the Equator to the Poles, are associated with polar amplification which is a well-established scientific fact. The present paper extends Brock and Xepapadeas (2017) to a non-cooperative framework with polar amplification, where regions decide emissions by maximizing own welfare. This can be regarded as a case of regional no...
متن کاملOn Feedbacks for Positive Discrete-time Singular Systems
In this work, N-periodic linear singular systems are considered. Feedbacks for obtaining positive N-periodic singular systems are analyzed. Some properties on the existence of these feedbacks are established. The concept of holdability of the setR+ is used for getting a positive trajectory of the closed-loop singular systems. This paper examines how feedbacks can be used to modify the trajector...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2005
ISSN: 1079-5642,1524-4636
DOI: 10.1161/01.atv.0000187463.91403.b2